Medical & Scientific Info

Latest RLS Research

This page is dedicated to current medical, scientific or research-based restless legs syndrome information. The latest information can be found in the scrolling box on the right side of the page.

Previous Research News

Read all about the breaking news in 2007 as the RLS gene variant was discovered.

Please note that most of the links below are outside sources. As you click on a link, you are leaving the RLS Foundation's website.

2009

• Mayo Clinic Researchers Find First Potential Pathogenic Mutation for Restless Legs Syndrome (July 21, 2009)
• Estrogen tied to restless legs during pregnancy (February 13, 2009)
• Celiac Disease Screening Recommended for RLS with Iron Deficiancy (February 9, 2009)
• Researchers Suspect a Novel Gene Is Causing Restless Legs Syndrome in a Large Family (February 3, 2009)
• XP13512 Shows Promising Results in Restless Legs Syndrome: Presented at AAPM (February 2, 2009)
• Pregnancy-related hormonal changes linked to increased risk of restless legs syndrome (February 1, 2009)
• Pain and Sleep: A Scientific and Clinical Conference, March 1-2, 2009, National Harbor, MD (January 14, 2009)
• GSK and Xenoport resubmit new drug application for Solzira™ in restless legs syndrome (January 9, 2009) 

2008

• UCB receives U.S. FDA Complete Response Letter for Neupro® in Restless Legs Syndrome (December 19, 2008)
• Spinal Anesthesia Doesn't Cause Restless Legs Syndrome (November 19, 2008)
• Why Allergy Meds Worsen Restless Legs Syndrome: Histaminergic Clinical and Autopsy Abnormalities in RLS (November 2008)
• GSK and XenoPort Announce Plans to Withdraw and Resubmit NDA for Solzira (November 17, 2008)
• GlaxoSmithKline and XenoPort file NDA for restless legs syndrome drug (September 17, 2008)
• Study shows RLS traced to genetics (August 22, 2008)
• Restless Legs a Family Familiar Test (August 19, 2008)
• Study: RLS Common in CKD Patients (July 21, 2008)
• MS Patients at Higher Risk for RLS (June 30, 2008)
• FDA Approves first generic Ropinirole (May 12, 2008)
• Neupro® Recommended For Approval In Europe For Restless Legs Syndrome (April 25, 2008)
• RLS and FibromyalgiaNational Fibromyalgia Assocation( April 18, 2008)
• Sleep Disturbance Reduced for Patients With Restless Legs Syndrome Taking Pramipexole: Presented at AAN (April 17, 2008)
• Data Presented at the American Academy of Neurology Show XP13512/GSK1838262 Significantly Improved Symptoms of Moderate-to-Severe Primary Restless Legs Syndrome (April 17, 2008)
• UCB partially recalls Parkinson's drug Neupro (March 20, 2008)
• UCB recalls Parkinson's patch, reviews 2008 outlook (March 20, 2008)
• Sleep Disorders Linked to Childhood Hyperactivity (March 19, 2008)
• XenoPort Announces Positive Results of a Phase 1 Clinical Trial of XP21279 (March 12, 2008)
• GlaxoSmithKline And XenoPort Report Positive Top-line Results Of Second Phase 3 Restless Legs Syndrome Trial For XP13512/GSK1838262 
• Prevalence of RLS in Korean adults (February 1, 2008)
• Restless legs syndrome doubles risk of stroke and heart disease (January 1, 2008)

2007

• Neupro^® Filed in Europe for the Treatment of Restless Legs Syndrome (December 5, 2007)
• New way to diagnose restless legs syndrome (Baton Rouge, LA)
• Restless legs syndrome may be associated with migraine (November 3, 2007)
• Restless legs syndrome affects nearly 2 percent of U.S./U.K. children (August 22, 2007)
• New Patch for RLS approved in UK but Not Yet USA
• GSK receives FDA approval letter for Requip CF (August 15, 2007)
• Restless Legs Syndrome: Prevalence and Impact in Children and Adolescents -- The PEDS REST Study - Abstract (August 2007)
• Restless Legs Syndrome: Prevalence and Impact in Children and Adolescents -- The PEDS REST Study - Press Release (August 2007)
• Genetic Risk Factors For Restless Legs Syndrome Identified For The First Time (July 22, 2007)
• Gene Variant for Restless Legs Syndrome Discovered (July 18, 2007)
• Restless legs syndrome linked to hypertension(June 14, 2007)
• Bacterial overgrowth in the gut, a factor in irritable bowel syndrome, may also be at work in RLS(May 25, 2007)
• FDA Approves First Drug for Treating Fibromyalgia(June 21, 2007)
• Results of Phase III clinical trial of experimental RLS drug(April 25, 2007)
• New study suggests RLS may increase risk of heart disease(April 9, 2007)
• Pergolide (Permax) voluntarily removed from the market(March 29, 2007)

Older

• (JADA Continuing Education) Restless legs syndrome Manifestations, treatment and dental implications (2006)
• FDA approves second drug for RLS(November 10, 2006)
• National survey shows RLS is under-recognized and poorly understood by US Adults(November 10, 2006)
• New Research Data on Pramipexole Show 95 Percent Effectiveness and Long-term Relief from the Symptoms of Restless Legs Syndrome(July 10, 2006)
• Requip first drug approved by FDA for RLS (May 5, 2005)